Disrupted Slit-Robo signalling results in membranous ventricular septum defects and bicuspid aortic valves

AIMS: The mesenchymal cushions lining the early embryonic heart undergo complex remodelling to form the membranous ventricular septum as well as the atrioventricular and semilunar valves in later life. Disruption of this process underlies the most common congenital heart defects. Here, we identified...

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Detalles Bibliográficos
Autores principales: Mommersteeg, Mathilda T.M., Yeh, Mason L., Parnavelas, John G., Andrews, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362403/
https://www.ncbi.nlm.nih.gov/pubmed/25691540
http://dx.doi.org/10.1093/cvr/cvv040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362403/
https://www.ncbi.nlm.nih.gov/pubmed/25691540
http://dx.doi.org/10.1093/cvr/cvv040

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