Cargando…

LTP-triggered cholesterol redistribution activates Cdc42 and drives AMPA receptor synaptic delivery

Neurotransmitter receptor trafficking during synaptic plasticity requires the concerted action of multiple signaling pathways and the protein transport machinery. However, little is known about the contribution of lipid metabolism during these processes. In this paper, we addressed the question of t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brachet, Anna, Norwood, Stephanie, Brouwers, Jos F., Palomer, Ernest, Helms, J. Bernd, Dotti, Carlos G., Esteban, José A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362467/ https://www.ncbi.nlm.nih.gov/pubmed/25753037 http://dx.doi.org/10.1083/jcb.201407122

Ejemplares similares

PICK1 links AMPA receptor stimulation to Cdc42
por: Rocca, Daniel L., et al.
Publicado: (2015)

AKAP150 Palmitoylation Regulates Synaptic Incorporation of Ca(2+)-Permeable AMPA Receptors to Control LTP
por: Purkey, Alicia M., et al.
Publicado: (2018)

PKA drives an increase in AMPA receptor unitary conductance during LTP in the hippocampus
por: Park, Pojeong, et al.
Publicado: (2021)

Postsynaptic Synaptotagmins Mediate AMPA Receptor Exocytosis During LTP
por: Wu, Dick, et al.
Publicado: (2017)

PIP(3)-Phldb2 is crucial for LTP regulating synaptic NMDA and AMPA receptor density and PSD95 turnover
por: Xie, Min-Jue, et al.
Publicado: (2019)

Brownian diffusion of AMPA receptors is sufficient to explain fast onset of LTP
por: Tolle, Dominic P, et al.
Publicado: (2010)

Cyclin Y inhibits plasticity-induced AMPA receptor exocytosis and LTP
por: Cho, Eunsil, et al.
Publicado: (2015)

Hippocampal LTP and contextual learning require surface diffusion of AMPA receptors
por: Penn, A.C., et al.
Publicado: (2017)

AMPA receptor trafficking and LTP: Carboxy-termini, amino-termini and TARPs
por: Díaz-Alonso, Javier, et al.
Publicado: (2021)

The roles of STP and LTP in synaptic encoding
por: Volianskis, Arturas, et al.
Publicado: (2013)

Different Forms of AMPA Receptor Mediated LTP and Their Correlation to the Spatial Working Memory Formation
por: Shimshek, Derya R., et al.
Publicado: (2017)

Loss of Cdc42 leads to defects in synaptic plasticity and remote memory recall
por: Kim, Il Hwan, et al.
Publicado: (2014)

Thrombin induces ischemic LTP (iLTP): implications for synaptic plasticity in the acute phase of ischemic stroke
por: Stein, Efrat Shavit, et al.
Publicado: (2015)

Drug-Driven AMPA Receptor Redistribution Mimicked by Selective Dopamine Neuron Stimulation
por: Brown, Matthew T. C., et al.
Publicado: (2010)

Excitotoxicity increases the release of 24S-hydroxycholesterol via CYP46A1 activation
por: Sodero, Alejandro, et al.
Publicado: (2013)

Hyperalgesia by synaptic long-term potentiation (LTP): an update
por: Sandkühler, Jürgen, et al.
Publicado: (2012)

LTP or LTD? Modeling the Influence of Stress on Synaptic Plasticity
por: Peters, Achim, et al.
Publicado: (2018)

Homer1 gene products orchestrate Ca(2+)-permeable AMPA receptor distribution and LTP expression
por: Rozov, Andrei, et al.
Publicado: (2012)

SUMOylation Is Required for Glycine-Induced Increases in AMPA Receptor Surface Expression (ChemLTP) in Hippocampal Neurons
por: Jaafari, Nadia, et al.
Publicado: (2013)

The Borg family of Cdc42 effector proteins Cdc42EP1–5
por: Farrugia, Aaron J., et al.
Publicado: (2016)

Cdc42 regulates Cdc42EP3 function in cancer-associated fibroblasts
por: Farrugia, Aaron J., et al.
Publicado: (2016)

G-protein coupled estrogen receptor (GPER1) activation promotes synaptic insertion of AMPA receptors and induction of chemical LTP at hippocampal temporoammonic-CA1 synapses
por: Clements, Leigh, et al.
Publicado: (2023)

Cdc42 turns the spindle
por: Leslie, Mitch
Publicado: (2008)

The first buds of Cdc42
por: Short, Ben
Publicado: (2015)

RNAi screen of Salmonella invasion shows role of COPI in membrane targeting of cholesterol and Cdc42
por: Misselwitz, Benjamin, et al.
Publicado: (2011)

Cdc42 Effector Protein 3 Interacts With Cdc42 in Regulating Xenopus Somite Segmentation
por: Kho, Mary, et al.
Publicado: (2019)

KIF13A drives AMPA receptor synaptic delivery for long-term potentiation via endosomal remodeling
por: Gutiérrez, Yolanda, et al.
Publicado: (2021)

Sensory-Induced Human LTP-Like Synaptic Plasticity – Using Visual Evoked Potentials to Explore the Relation Between LTP-Like Synaptic Plasticity and Visual Perceptual Learning
por: Lengali, Lilly, et al.
Publicado: (2021)

AMPA Receptor Activation Causes Silencing of AMPA Receptor-Mediated Synaptic Transmission in the Developing Hippocampus
por: Wasling, Pontus, et al.
Publicado: (2012)

Wnt Signaling Mediates LTP-Dependent Spine Plasticity and AMPAR Localization through Frizzled-7 Receptors
por: McLeod, Faye, et al.
Publicado: (2018)

Synaptotagmin-IV Modulates Synaptic Function and LTP by Regulating BDNF Release
por: Dean, Camin, et al.
Publicado: (2009)

Secreted Amyloid Precursor Protein-Alpha Enhances LTP Through the Synthesis and Trafficking of Ca(2+)-Permeable AMPA Receptors
por: Livingstone, Rhys W., et al.
Publicado: (2021)

Homeostatic synaptic scaling: molecular regulators of synaptic AMPA-type glutamate receptors
por: Chowdhury, Dhrubajyoti, et al.
Publicado: (2018)

The role of AMPA receptors in postsynaptic mechanisms of synaptic plasticity
por: Chater, Thomas E., et al.
Publicado: (2014)

Hebbian and homeostatic synaptic plasticity of AMPA receptors in epileptogenesis
por: Curia, Giulia
Publicado: (2023)

Rapid Redistribution of Synaptic PSD-95 in the Neocortex In Vivo
por: Gray, Noah W, et al.
Publicado: (2006)

Spatial analysis of Cdc42 activity reveals a role for plasma membrane–associated Cdc42 in centrosome regulation
por: Herrington, Kari A., et al.
Publicado: (2017)

Acute intracerebral treatment with amyloid-beta (1–42) alters the profile of neuronal oscillations that accompany LTP induction and results in impaired LTP in freely behaving rats
por: Kalweit, Alexander Nikolai, et al.
Publicado: (2015)

PIP(3) controls synaptic function by maintaining AMPA receptor clustering at the postsynaptic membrane
por: Arendt, Kristin L., et al.
Publicado: (2009)

The modular cross-synaptic nature of LTP/LTD following on-going neural activity
por: Loebel, Alex, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_d168d7jara79kiffukaul7msi4