Deregulation of sertoli and leydig cells function in patients with klinefelter syndrome as evidenced by testis transcriptome analysis

BACKGROUND: Klinefelter Syndrome (KS) is the most common abnormality of sex chromosomes (47,XXY) and represents the first genetic cause of male infertility. Mechanisms leading to KS testis degeneration are still not completely defined but considered to be mainly the result of germ cells loss. In ord...

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Detalles Bibliográficos
Autores principales: D’Aurora, Marco, Ferlin, Alberto, Di Nicola, Marta, Garolla, Andrea, De Toni, Luca, Franchi, Sara, Palka, Giandomenico, Foresta, Carlo, Stuppia, Liborio, Gatta, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362638/
https://www.ncbi.nlm.nih.gov/pubmed/25879484
http://dx.doi.org/10.1186/s12864-015-1356-0

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