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Evolution of lysine acetylation in the RNA polymerase II C-terminal domain

BACKGROUND: RPB1, the largest subunit of RNA polymerase II, contains a highly modifiable C-terminal domain (CTD) that consists of variations of a consensus heptad repeat sequence (Y(1)S(2)P(3)T(4)S(5)P(6)S(7)). The consensus CTD repeat motif and tandem organization represent the ancestral state of e...

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Detalles Bibliográficos
Autores principales: Simonti, Corinne N, Pollard, Katherine S, Schröder, Sebastian, He, Daniel, Bruneau, Benoit G, Ott, Melanie, Capra, John A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362643/
https://www.ncbi.nlm.nih.gov/pubmed/25887984
http://dx.doi.org/10.1186/s12862-015-0327-z