Liriodenine, an aporphine alkaloid from Enicosanthellum pulchrum, inhibits proliferation of human ovarian cancer cells through induction of apoptosis via the mitochondrial signaling pathway and blocking cell cycle progression

Enicosanthellum pulchrum is a tropical plant from Malaysia and belongs to the Annonaceae family. This plant is rich in isoquinoline alkaloids. In the present study, liriodenine, an isoquinoline alkaloid, was examined as a potential anticancer agent, particularly in ovarian cancer. Liriodenine was is...

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Detalles Bibliográficos
Autores principales: Nordin, Noraziah, Majid, Nazia Abdul, Hashim, Najihah Mohd, Rahman, Mashitoh Abd, Hassan, Zalila, Ali, Hapipah Mohd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362660/
https://www.ncbi.nlm.nih.gov/pubmed/25792804
http://dx.doi.org/10.2147/DDDT.S77727

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