Phosphorylated α-synuclein in Parkinson’s disease: correlation depends on disease severity

INTRODUCTION: α-Synuclein (α-syn) is a key protein in Parkinson’s disease (PD), and one of its phosphorylated forms, pS129, is higher in PD patients than healthy controls. However, few studies have examined its levels in longitudinally collected cerebrospinal fluid (CSF) or in preclinical cases. In...

Descripción completa

Detalles Bibliográficos
Autores principales: Stewart, Tessandra, Sossi, Vesna, Aasly, Jan O, Wszolek, Zbigniew K, Uitti, Ryan J, Hasegawa, Kazuko, Yokoyama, Teruo, Zabetian, Cyrus P, Leverenz, James B, Stoessl, Alexander Jon, Wang, Yu, Ginghina, Carmen, Liu, Changqin, Cain, Kevin C, Auinger, Peggy, Kang, Un Jung, Jensen, Poul Henning, Shi, Min, Zhang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362824/
https://www.ncbi.nlm.nih.gov/pubmed/25637461
http://dx.doi.org/10.1186/s40478-015-0185-3

Ejemplares similares

Ejemplares similares