A Genome-Scale Vector Resource Enables High-Throughput Reverse Genetic Screening in a Malaria Parasite

The genome-wide identification of gene functions in malaria parasites is hampered by a lack of reverse genetic screening methods. We present a large-scale resource of barcoded vectors with long homology arms for effective modification of the Plasmodium berghei genome. Cotransfecting dozens of vector...

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Detalles Bibliográficos
Autores principales: Gomes, Ana Rita, Bushell, Ellen, Schwach, Frank, Girling, Gareth, Anar, Burcu, Quail, Michael A., Herd, Colin, Pfander, Claudia, Modrzynska, Katarzyna, Rayner, Julian C., Billker, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362957/
https://www.ncbi.nlm.nih.gov/pubmed/25732065
http://dx.doi.org/10.1016/j.chom.2015.01.014

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