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Mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor in a ferret
A 5-year-old male ferret presented with an enlarged canalicular testis in the left inguinal region. Microscopically, the enlarged testis consisted of a diffuse intimately admixed proliferation of c-kit-positive germ cell-like and Wilms tumor-1 protein-positive Sertoli cell-like components, but no Ca...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Veterinary Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363027/ https://www.ncbi.nlm.nih.gov/pubmed/25311985 http://dx.doi.org/10.1292/jvms.14-0435 |
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author | INOUE, Saki YONEMARU, Kayoko YANAI, Tokuma SAKAI, Hiroki |
author_facet | INOUE, Saki YONEMARU, Kayoko YANAI, Tokuma SAKAI, Hiroki |
author_sort | INOUE, Saki |
collection | PubMed |
description | A 5-year-old male ferret presented with an enlarged canalicular testis in the left inguinal region. Microscopically, the enlarged testis consisted of a diffuse intimately admixed proliferation of c-kit-positive germ cell-like and Wilms tumor-1 protein-positive Sertoli cell-like components, but no Call-Exner body was detected. In addition, the compact proliferation of steroidogenic acute regulatory protein-intense positive interstitial cells was identified in a separate peripheral area of the mass. Based on histopathological and immunohistochemical findings, the tumor was diagnosed as a mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor. |
format | Online Article Text |
id | pubmed-4363027 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | The Japanese Society of Veterinary Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-43630272015-03-19 Mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor in a ferret INOUE, Saki YONEMARU, Kayoko YANAI, Tokuma SAKAI, Hiroki J Vet Med Sci Pathology A 5-year-old male ferret presented with an enlarged canalicular testis in the left inguinal region. Microscopically, the enlarged testis consisted of a diffuse intimately admixed proliferation of c-kit-positive germ cell-like and Wilms tumor-1 protein-positive Sertoli cell-like components, but no Call-Exner body was detected. In addition, the compact proliferation of steroidogenic acute regulatory protein-intense positive interstitial cells was identified in a separate peripheral area of the mass. Based on histopathological and immunohistochemical findings, the tumor was diagnosed as a mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor. The Japanese Society of Veterinary Science 2014-10-13 2015-02 /pmc/articles/PMC4363027/ /pubmed/25311985 http://dx.doi.org/10.1292/jvms.14-0435 Text en ©2015 The Japanese Society of Veterinary Science http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. |
spellingShingle | Pathology INOUE, Saki YONEMARU, Kayoko YANAI, Tokuma SAKAI, Hiroki Mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor in a ferret |
title | Mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor in a ferret |
title_full | Mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor in a ferret |
title_fullStr | Mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor in a ferret |
title_full_unstemmed | Mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor in a ferret |
title_short | Mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor in a ferret |
title_sort | mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor in a ferret |
topic | Pathology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363027/ https://www.ncbi.nlm.nih.gov/pubmed/25311985 http://dx.doi.org/10.1292/jvms.14-0435 |
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