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Mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor in a ferret

A 5-year-old male ferret presented with an enlarged canalicular testis in the left inguinal region. Microscopically, the enlarged testis consisted of a diffuse intimately admixed proliferation of c-kit-positive germ cell-like and Wilms tumor-1 protein-positive Sertoli cell-like components, but no Ca...

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Autores principales: INOUE, Saki, YONEMARU, Kayoko, YANAI, Tokuma, SAKAI, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363027/
https://www.ncbi.nlm.nih.gov/pubmed/25311985
http://dx.doi.org/10.1292/jvms.14-0435
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author INOUE, Saki
YONEMARU, Kayoko
YANAI, Tokuma
SAKAI, Hiroki
author_facet INOUE, Saki
YONEMARU, Kayoko
YANAI, Tokuma
SAKAI, Hiroki
author_sort INOUE, Saki
collection PubMed
description A 5-year-old male ferret presented with an enlarged canalicular testis in the left inguinal region. Microscopically, the enlarged testis consisted of a diffuse intimately admixed proliferation of c-kit-positive germ cell-like and Wilms tumor-1 protein-positive Sertoli cell-like components, but no Call-Exner body was detected. In addition, the compact proliferation of steroidogenic acute regulatory protein-intense positive interstitial cells was identified in a separate peripheral area of the mass. Based on histopathological and immunohistochemical findings, the tumor was diagnosed as a mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor.
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spelling pubmed-43630272015-03-19 Mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor in a ferret INOUE, Saki YONEMARU, Kayoko YANAI, Tokuma SAKAI, Hiroki J Vet Med Sci Pathology A 5-year-old male ferret presented with an enlarged canalicular testis in the left inguinal region. Microscopically, the enlarged testis consisted of a diffuse intimately admixed proliferation of c-kit-positive germ cell-like and Wilms tumor-1 protein-positive Sertoli cell-like components, but no Call-Exner body was detected. In addition, the compact proliferation of steroidogenic acute regulatory protein-intense positive interstitial cells was identified in a separate peripheral area of the mass. Based on histopathological and immunohistochemical findings, the tumor was diagnosed as a mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor. The Japanese Society of Veterinary Science 2014-10-13 2015-02 /pmc/articles/PMC4363027/ /pubmed/25311985 http://dx.doi.org/10.1292/jvms.14-0435 Text en ©2015 The Japanese Society of Veterinary Science http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License.
spellingShingle Pathology
INOUE, Saki
YONEMARU, Kayoko
YANAI, Tokuma
SAKAI, Hiroki
Mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor in a ferret
title Mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor in a ferret
title_full Mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor in a ferret
title_fullStr Mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor in a ferret
title_full_unstemmed Mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor in a ferret
title_short Mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor in a ferret
title_sort mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor in a ferret
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363027/
https://www.ncbi.nlm.nih.gov/pubmed/25311985
http://dx.doi.org/10.1292/jvms.14-0435
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