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The absence of the leukotriene B(4) receptor BLT1 attenuates peripheral inflammation and spinal nociceptive processing following intraplantar formalin injury
BACKGROUND: Leukotriene B(4) (LTB(4)) is a potent lipid mediator of inflammation, and its biological effects are mediated primarily through the high affinity LTB(4) receptor BLT1. Although numerous studies have reported that LTB(4)-BLT1 signaling is involved in inflammatory diseases, the role of BLT...
Autores principales: | Asahara, Miho, Ito, Nobuko, Yokomizo, Takehiko, Nakamura, Motonao, Shimizu, Takao, Yamada, Yoshitsugu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363055/ https://www.ncbi.nlm.nih.gov/pubmed/25889478 http://dx.doi.org/10.1186/s12990-015-0010-9 |
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