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Dual Specificity Phosphatase 6 (DUSP6) regulates CD4+ T cell functions and restrains the spontaneous colitis in IL-10 deficient mice

Mitogen-activated protein kinase (MAPK) phosphatases are dual-specificity phosphatases (DUSPs) that dephosphorylate phosphothreonine and phosphotyrosine residues within MAPKs. DUSP6 preferentially dephosphorylates extracellular signal-regulated kinase 1 and 2 (ERK1/2) rendering them inactive. Here,...

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Detalles Bibliográficos
Autores principales:	Bertin, Samuel, Lozano-Ruiz, Beatriz, Bachiller, Victoria, García-Martínez, Irma, Herdman, Scott, Zapater, Pedro, Francés, Rubén, Such, José, Lee, Jongdae, Raz, Eyal, González-Navajas, José M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363301/ https://www.ncbi.nlm.nih.gov/pubmed/25227984 http://dx.doi.org/10.1038/mi.2014.84

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