Cargando…

Canolol Inhibits Gastric Tumors Initiation and Progression through COX-2/PGE2 Pathway in K19-C2mE Transgenic Mice

4-vinyl-2, 6-dimethoxyphenol (canolol) is an antioxidant phenolic compound extracted from crude canola oil. In current research, K19-C2mE transgenic mice, developing hyperplastic tumors spontaneously in the glandular stomach, were used to study the mechanisms involved in the anti-inflammation and an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cao, Donghui, Jiang, Jing, Tsukamoto, Tetsuya, Liu, Ruming, Ma, Lin, Jia, Zhifang, Kong, Fei, Oshima, Masanobu, Cao, Xueyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363315/ https://www.ncbi.nlm.nih.gov/pubmed/25781635 http://dx.doi.org/10.1371/journal.pone.0120938

Ejemplares similares

Anticancer effects of 4-vinyl-2,6-dimethoxyphenol (canolol) against SGC-7901 human gastric carcinoma cells
por: JIANG, JING, et al.
Publicado: (2013)

COX-2-PGE(2)-EPs in gynecological cancers
por: Ye, Yao, et al.
Publicado: (2020)

18β-glycyrrhetinic acid suppresses gastric cancer by activation of miR-149-3p-Wnt-1 signaling
por: Cao, Donghui, et al.
Publicado: (2016)

Regulated Expression of PTPRJ by COX-2/PGE(2) Axis in Endothelial Cells
por: Xu, Xiaobing, et al.
Publicado: (2014)

Pleiotropic effects of the COX-2/PGE2 axis in the glioblastoma tumor microenvironment
por: Dean, Phillip T., et al.
Publicado: (2023)

Formononetin inhibits enterovirus 71 replication by regulating COX- 2/PGE(2) expression
por: Wang, Huiqiang, et al.
Publicado: (2015)

IL-33 facilitates proliferation of colorectal cancer dependent on COX2/PGE(2)
por: Li, Yongkui, et al.
Publicado: (2018)

Role of COX-2/PGE2 Mediated Inflammation in Oral Squamous Cell Carcinoma
por: Nasry, Walaa Hamed Shaker, et al.
Publicado: (2018)

Improving VEGF-targeted therapies through inhibition of COX-2/PGE(2) signaling
por: Xu, Lihong, et al.
Publicado: (2014)

COX2 regulates senescence secretome composition and senescence surveillance through PGE(2)
por: Gonçalves, Susana, et al.
Publicado: (2021)

Dedifferentiation of Human Cardiac Myofibroblasts Is Independent of Activation of COX-2/PGE(2) Pathway
por: Luu, Vy Tran, et al.
Publicado: (2022)

COX-2/PGE2 upregulation contributes to the chromosome 17p-deleted lymphoma
por: Qi, Lu, et al.
Publicado: (2023)

NDRG2 Controls COX-2/PGE(2)-Mediated Breast Cancer Cell Migration and Invasion
por: Kim, Myung-Jin, et al.
Publicado: (2014)

Involvement of COX-2/PGE(2) Pathway in the Upregulation of MMP-9 Expression in Pancreatic Cancer
por: Bu, Xianmin, et al.
Publicado: (2011)

Involvement of COX-2/PGE(2) signalling in hypoxia-induced angiogenic response in endothelial cells
por: Zhao, Lixing, et al.
Publicado: (2012)

Correction to: IL-33 facilitates proliferation of colorectal cancer dependent on COX2/PGE(2)
por: Li, Yongkui, et al.
Publicado: (2020)

The Role of COX-2 and PGE2 in the Regulation of Immunomodulation and Other Functions of Mesenchymal Stromal Cells
por: Kulesza, Agnieszka, et al.
Publicado: (2023)

Growth and adherence of Staphylococcus aureus were enhanced through the PGE(2) produced by the activated COX-2/PGE(2) pathway of infected oral epithelial cells
por: Wang, Yuxia, et al.
Publicado: (2017)

Positive acceleration adaptive training attenuates gastric ischemia-reperfusion injury through COX-2 and PGE2 expression
por: Chen, Ying, et al.
Publicado: (2019)

Norepinephrine enhances the LPS-induced expression of COX-2 and secretion of PGE(2 )in primary rat microglia
por: Schlachetzki, Johannes CM, et al.
Publicado: (2010)

Activation of COX-2/PGE(2) Promotes Sapovirus Replication via the Inhibition of Nitric Oxide Production
por: Alfajaro, Mia Madel, et al.
Publicado: (2017)

Atorvastatin attenuates plaque vulnerability by downregulation of EMMPRIN expression via COX-2/PGE2 pathway
por: Liang, Xing, et al.
Publicado: (2017)

Mesenchymal stem cells inhibited the differentiation of MDSCs via COX2/PGE2 in experimental sialadenitis
por: Qi, Jingjing, et al.
Publicado: (2020)

Targeting of the COX-2/PGE2 axis enhances the antitumor activity of T7 peptide in vitro and in vivo
por: Yang, Jianrong, et al.
Publicado: (2021)

The Protective Effects of 18β-Glycyrrhetinic Acid on Helicobacter pylori-Infected Gastric Mucosa in Mongolian Gerbils
por: Cao, Donghui, et al.
Publicado: (2016)

Inflammation in gastric cancer: Interplay of the COX‐2/prostaglandin E(2) and Toll‐like receptor/MyD88 pathways
por: Echizen, Kanae, et al.
Publicado: (2016)

Targeting COX-2/PGE(2) Pathway in HIPK2 Knockdown Cancer Cells: Impact on Dendritic Cell Maturation
por: Garufi, Alessia, et al.
Publicado: (2012)

Regulation of Matrix Metalloproteinase-2 Activity by COX-2-PGE2-pAKT Axis Promotes Angiogenesis in Endometriosis
por: Jana, Sayantan, et al.
Publicado: (2016)

COX-2/PGE2: molecular ambassadors of Kaposi's sarcoma-associated herpes virus oncoprotein-v-FLIP
por: Sharma-Walia, N, et al.
Publicado: (2012)

Key role of the positive feedback between PGE(2) and COX2 in the biology of myeloid-derived suppressor cells
por: Obermajer, Nataŝa, et al.
Publicado: (2012)

COX-2-derived PGE(2) triggers hyperplastic renin expression and hyperreninemia in aldosterone synthase-deficient mice
por: Karger, Christian, et al.
Publicado: (2018)

Feline calicivirus- and murine norovirus-induced COX-2/PGE(2) signaling pathway has proviral effects
por: Alfajaro, Mia Madel, et al.
Publicado: (2018)

Resveratrol treatment inhibits acute pharyngitis in the mice model through inhibition of PGE2/COX-2 expression
por: Yu, Zhaoyan, et al.
Publicado: (2018)

PPARβ/δ Augments IL-1β-Induced COX-2 Expression and PGE2 Biosynthesis in Human Mesangial Cells via the Activation of SIRT1
por: Li, Yaqing, et al.
Publicado: (2022)

Effects of High-Canolol Phenolic Extracts on Fragrant Rapeseed Oil Quality and Flavor Compounds during Frying
por: Cao, Lili, et al.
Publicado: (2023)

Rapidoxy® 100: A Solvent-Free Pre-treatment for Production of Canolol
por: Nandasiri, Ruchira, et al.
Publicado: (2021)

Nitrooleic Acid Protects against Cisplatin Nephropathy: Role of COX-2/mPGES-1/PGE(2) Cascade
por: Wang, Haiping, et al.
Publicado: (2015)

Effect of COX-2 inhibition on tendon-to-bone healing and PGE2 concentration after anterior cruciate ligament reconstruction
por: Sauerschnig, Martin, et al.
Publicado: (2018)

MRP4 regulates ENaC-dependent CREB/COX-2/PGE(2) signaling during embryo implantation
por: Chen, Jun-Jiang, et al.
Publicado: (2017)

Rheumatoid arthritis synovial fibroblasts promote TREM-1 expression in monocytes via COX-2/PGE(2) pathway
por: Peng, Anping, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_etgl6sc701aap6730areepa0b7