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Adaptive Resistance in Bacteria Requires Epigenetic Inheritance, Genetic Noise, and Cost of Efflux Pumps

Adaptive resistance emerges when populations of bacteria are subjected to gradual increases of antibiotics. It is characterized by a rapid emergence of resistance and fast reversibility to the non-resistant phenotype when the antibiotic is removed from the medium. Recent work shows that adaptive res...

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Detalles Bibliográficos
Autores principales: Motta, Santiago Sandoval, Cluzel, Philippe, Aldana, Maximino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363326/
https://www.ncbi.nlm.nih.gov/pubmed/25781931
http://dx.doi.org/10.1371/journal.pone.0118464