COMP-Ang1 Potentiates EPC Treatment of Ischemic Brain Injury by Enhancing Angiogenesis Through Activating AKT-mTOR Pathway and Promoting Vascular Migration Through Activating Tie2-FAK Pathway

Successful recovery from brain ischemia is limited due to poor vascularization surrounding the ischemic zone. Cell therapy with strong angiogenic factors could be an effective strategy to rescue the ischemic brain. We investigated whether cartilage oligomeric matrix protein (COMP)-Ang1, a soluble, s...

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Detalles Bibliográficos
Autores principales: Moon, Hyo Eun, Byun, Kyunghee, Park, Hyung Woo, Kim, Jin Hyun, Hur, Jin, Park, Joong Shin, Jun, Jong Kwan, Kim, Hyo-Soo, Paek, Seung Leal, Kim, In Keyoung, Hwang, Jae Ha, Kim, Jin Wook, Kim, Dong Gyu, Sung, Young Chul, Koh, Gou-Young, Song, Chang W, Lee, Bonghee, Paek, Sun Ha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363334/
https://www.ncbi.nlm.nih.gov/pubmed/25792870
http://dx.doi.org/10.5607/en.2015.24.1.55

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