Insulin Receptor Signaling in the GnRH Neuron Plays a Role in the Abnormal GnRH Pulsatility of Obese Female Mice

Infertility associated with obesity is characterized by abnormal hormone release from reproductive tissues in the hypothalamus, pituitary, and ovary. These tissues maintain insulin sensitivity upon peripheral insulin resistance. Insulin receptor signaling may play a role in the dysregulation of gona...

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Detalles Bibliográficos
Autores principales: DiVall, Sara A., Herrera, Danny, Sklar, Bonnie, Wu, Sheng, Wondisford, Fredric, Radovick, Sally, Wolfe, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363364/
https://www.ncbi.nlm.nih.gov/pubmed/25780937
http://dx.doi.org/10.1371/journal.pone.0119995

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