Cargando…
MITF in melanoma: mechanisms behind its expression and activity
MITF (microphthalmia-associated transcription factor) represents a melanocytic lineage-specific transcription factor whose role is profoundly extended in malignant melanoma. Over the last few years, the function of MITF has been tightly connected to plasticity of melanoma cells. MITF participates in...
Autores principales: | Hartman, Mariusz L., Czyz, Malgorzata |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Basel
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363485/ https://www.ncbi.nlm.nih.gov/pubmed/25433395 http://dx.doi.org/10.1007/s00018-014-1791-0 |
Ejemplares similares
-
Parthenolide induces MITF-M downregulation and senescence in patient-derived MITF-M(high) melanoma cell populations
por: Hartman, Mariusz L., et al.
Publicado: (2016) -
TYRP1 mRNA level is stable and MITF-M-independent in drug-naïve, vemurafenib- and trametinib-resistant BRAF(V600E) melanoma cells
por: Hartman, Mariusz L., et al.
Publicado: (2019) -
MCL-1, BCL-X(L) and MITF Are Diversely Employed in Adaptive Response of Melanoma Cells to Changes in Microenvironment
por: Hartman, Mariusz L., et al.
Publicado: (2015) -
Trametinib-Resistant Melanoma Cells Displaying MITF(high)/NGFR(low)/IL-8(low) Phenotype Are Highly Responsive to Alternating Periods of Drug Withdrawal and Drug Rechallenge
por: Koziej, Paulina, et al.
Publicado: (2023) -
Gene Expression Profiling Identifies Microphthalmia-Associated Transcription Factor (MITF) and Dickkopf-1 (DKK1) as Regulators of Microenvironment-Driven Alterations in Melanoma Phenotype
por: Hartman, Mariusz L., et al.
Publicado: (2014)