A Novel Approach to Delayed-Start Analyses for Demonstrating Disease-Modifying Effects in Alzheimer’s Disease

One method for demonstrating disease modification is a delayed-start design, consisting of a placebo-controlled period followed by a delayed-start period wherein all patients receive active treatment. To address methodological issues in previous delayed-start approaches, we propose a new method that...

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Detalles Bibliográficos
Autores principales: Liu-Seifert, Hong, Andersen, Scott W., Lipkovich, Ilya, Holdridge, Karen C., Siemers, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363486/
https://www.ncbi.nlm.nih.gov/pubmed/25781335
http://dx.doi.org/10.1371/journal.pone.0119632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363486/
https://www.ncbi.nlm.nih.gov/pubmed/25781335
http://dx.doi.org/10.1371/journal.pone.0119632

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