Cargando…
Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients
Sentinel lymph node biopsy (SLNB) emerged in the 1990s as a new technique in the surgical management of the axilla for patients with early breast cancer, resulting in lower complication rates and better quality of life than axillary lymph node dissection (ALND). Today SLNB is firmly established in t...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363495/ https://www.ncbi.nlm.nih.gov/pubmed/25821800 http://dx.doi.org/10.1155/2015/405949 |
_version_ | 1782361918442307584 |
---|---|
author | Assi, Hazem Sbaity, Eman Abdelsalam, Mahmoud Shamseddine, Ali |
author_facet | Assi, Hazem Sbaity, Eman Abdelsalam, Mahmoud Shamseddine, Ali |
author_sort | Assi, Hazem |
collection | PubMed |
description | Sentinel lymph node biopsy (SLNB) emerged in the 1990s as a new technique in the surgical management of the axilla for patients with early breast cancer, resulting in lower complication rates and better quality of life than axillary lymph node dissection (ALND). Today SLNB is firmly established in the armamentarium of clinicians treating breast cancer, but several questions remain. The goal of this paper is to review recent work addressing 4 questions that have been the subject of debate in the use of SLNB in the past few years: (a) What is the implication of finding micrometastases in the sentinel nodes? (b) Is ALND necessary in all patients who have a positive SLNB? (c) How accurate is SLNB after neoadjuvant therapy? (d) Can SLNB be used to stage the axilla in locally recurrent breast cancer following breast surgery with or without prior axillary surgery? |
format | Online Article Text |
id | pubmed-4363495 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-43634952015-03-29 Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients Assi, Hazem Sbaity, Eman Abdelsalam, Mahmoud Shamseddine, Ali Biomed Res Int Review Article Sentinel lymph node biopsy (SLNB) emerged in the 1990s as a new technique in the surgical management of the axilla for patients with early breast cancer, resulting in lower complication rates and better quality of life than axillary lymph node dissection (ALND). Today SLNB is firmly established in the armamentarium of clinicians treating breast cancer, but several questions remain. The goal of this paper is to review recent work addressing 4 questions that have been the subject of debate in the use of SLNB in the past few years: (a) What is the implication of finding micrometastases in the sentinel nodes? (b) Is ALND necessary in all patients who have a positive SLNB? (c) How accurate is SLNB after neoadjuvant therapy? (d) Can SLNB be used to stage the axilla in locally recurrent breast cancer following breast surgery with or without prior axillary surgery? Hindawi Publishing Corporation 2015 2015-03-03 /pmc/articles/PMC4363495/ /pubmed/25821800 http://dx.doi.org/10.1155/2015/405949 Text en Copyright © 2015 Hazem Assi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Assi, Hazem Sbaity, Eman Abdelsalam, Mahmoud Shamseddine, Ali Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients |
title | Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients |
title_full | Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients |
title_fullStr | Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients |
title_full_unstemmed | Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients |
title_short | Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients |
title_sort | controversial indications for sentinel lymph node biopsy in breast cancer patients |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363495/ https://www.ncbi.nlm.nih.gov/pubmed/25821800 http://dx.doi.org/10.1155/2015/405949 |
work_keys_str_mv | AT assihazem controversialindicationsforsentinellymphnodebiopsyinbreastcancerpatients AT sbaityeman controversialindicationsforsentinellymphnodebiopsyinbreastcancerpatients AT abdelsalammahmoud controversialindicationsforsentinellymphnodebiopsyinbreastcancerpatients AT shamseddineali controversialindicationsforsentinellymphnodebiopsyinbreastcancerpatients |