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Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients

Sentinel lymph node biopsy (SLNB) emerged in the 1990s as a new technique in the surgical management of the axilla for patients with early breast cancer, resulting in lower complication rates and better quality of life than axillary lymph node dissection (ALND). Today SLNB is firmly established in t...

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Autores principales: Assi, Hazem, Sbaity, Eman, Abdelsalam, Mahmoud, Shamseddine, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363495/
https://www.ncbi.nlm.nih.gov/pubmed/25821800
http://dx.doi.org/10.1155/2015/405949
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author Assi, Hazem
Sbaity, Eman
Abdelsalam, Mahmoud
Shamseddine, Ali
author_facet Assi, Hazem
Sbaity, Eman
Abdelsalam, Mahmoud
Shamseddine, Ali
author_sort Assi, Hazem
collection PubMed
description Sentinel lymph node biopsy (SLNB) emerged in the 1990s as a new technique in the surgical management of the axilla for patients with early breast cancer, resulting in lower complication rates and better quality of life than axillary lymph node dissection (ALND). Today SLNB is firmly established in the armamentarium of clinicians treating breast cancer, but several questions remain. The goal of this paper is to review recent work addressing 4 questions that have been the subject of debate in the use of SLNB in the past few years: (a) What is the implication of finding micrometastases in the sentinel nodes? (b) Is ALND necessary in all patients who have a positive SLNB? (c) How accurate is SLNB after neoadjuvant therapy? (d) Can SLNB be used to stage the axilla in locally recurrent breast cancer following breast surgery with or without prior axillary surgery?
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spelling pubmed-43634952015-03-29 Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients Assi, Hazem Sbaity, Eman Abdelsalam, Mahmoud Shamseddine, Ali Biomed Res Int Review Article Sentinel lymph node biopsy (SLNB) emerged in the 1990s as a new technique in the surgical management of the axilla for patients with early breast cancer, resulting in lower complication rates and better quality of life than axillary lymph node dissection (ALND). Today SLNB is firmly established in the armamentarium of clinicians treating breast cancer, but several questions remain. The goal of this paper is to review recent work addressing 4 questions that have been the subject of debate in the use of SLNB in the past few years: (a) What is the implication of finding micrometastases in the sentinel nodes? (b) Is ALND necessary in all patients who have a positive SLNB? (c) How accurate is SLNB after neoadjuvant therapy? (d) Can SLNB be used to stage the axilla in locally recurrent breast cancer following breast surgery with or without prior axillary surgery? Hindawi Publishing Corporation 2015 2015-03-03 /pmc/articles/PMC4363495/ /pubmed/25821800 http://dx.doi.org/10.1155/2015/405949 Text en Copyright © 2015 Hazem Assi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Assi, Hazem
Sbaity, Eman
Abdelsalam, Mahmoud
Shamseddine, Ali
Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients
title Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients
title_full Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients
title_fullStr Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients
title_full_unstemmed Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients
title_short Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients
title_sort controversial indications for sentinel lymph node biopsy in breast cancer patients
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363495/
https://www.ncbi.nlm.nih.gov/pubmed/25821800
http://dx.doi.org/10.1155/2015/405949
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