Combined Epidermal Growth Factor Receptor and Beclin1 Autophagic Protein Expression Analysis Identifies Different Clinical Presentations, Responses to Chemo- and Radiotherapy, and Prognosis in Glioblastoma

Dysregulated EGFR in glioblastoma may inactivate the key autophagy protein Beclin1. Each of high EGFR and low Beclin1 protein expression, independently, has been associated with tumor progression and poor prognosis. High (H) compared to low (L) expression of EGFR and Beclin1 is here correlated with...

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Detalles Bibliográficos
Autores principales: Tini, Paolo, Belmonte, Giuseppe, Toscano, Marzia, Miracco, Clelia, Palumbo, Silvia, Pastina, Pierpaolo, Battaglia, Giuseppe, Nardone, Valerio, Butorano, Marie Aimée Gloria Munezero, Masucci, Armando, Cerase, Alfonso, Pirtoli, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363549/
https://www.ncbi.nlm.nih.gov/pubmed/25821789
http://dx.doi.org/10.1155/2015/208076

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