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Tumor Progression Locus 2 Differentially Regulates IFNγ and IL-17 Production by Effector CD4(+) T Cells in a T Cell Transfer Model of Colitis
Autoimmune diseases are approaching epidemic levels, estimated to affect 5–8% of the population. A number of autoimmune diseases are believed to be driven by autoreactive T cells, specifically by T helper 1 (Th1) cells and T helper 17 (Th17) cells. One molecule gaining interest as a therapeutic targ...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363566/ https://www.ncbi.nlm.nih.gov/pubmed/25781948 http://dx.doi.org/10.1371/journal.pone.0119885 |