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Tumor Progression Locus 2 Differentially Regulates IFNγ and IL-17 Production by Effector CD4(+) T Cells in a T Cell Transfer Model of Colitis

Autoimmune diseases are approaching epidemic levels, estimated to affect 5–8% of the population. A number of autoimmune diseases are believed to be driven by autoreactive T cells, specifically by T helper 1 (Th1) cells and T helper 17 (Th17) cells. One molecule gaining interest as a therapeutic targ...

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Detalles Bibliográficos
Autores principales:	Acuff, Nicole V., Li, Xin, Kirkland, Rebecca, Nagy, Tamas, Watford, Wendy T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363566/ https://www.ncbi.nlm.nih.gov/pubmed/25781948 http://dx.doi.org/10.1371/journal.pone.0119885

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