Cargando…

Nicotinamide Exerts Antioxidative Effects on Senescent Cells

Nicotinamide (NAM) has been shown to suppress reactive oxygen species (ROS) production in primary human fibroblasts, thereby extending their replicative lifespan when added to the medium during long-term cultivation. Based on this finding, NAM is hypothesized to affect cellular senescence progressio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kwak, Ju Yeon, Ham, Hyun Joo, Kim, Cheol Min, Hwang, Eun Seong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363722/ https://www.ncbi.nlm.nih.gov/pubmed/25600149 http://dx.doi.org/10.14348/molcells.2015.2253

Ejemplares similares

Nicotinamide mononucleotide ameliorates senescence in alveolar epithelial cells
por: Fang, Tingting, et al.
Publicado: (2021)

Antioxidant effect of nicotinamide mononucleotide in tendinopathy
por: Yamaura, Kohei, et al.
Publicado: (2022)

Possible Adverse Effects of High-Dose Nicotinamide: Mechanisms and Safety Assessment
por: Hwang, Eun Seong, et al.
Publicado: (2020)

Flavonoids in Decorticated Sorghum Grains Exert Antioxidant, Antidiabetic and Antiobesity Activities
por: Ofosu, Fred Kwame, et al.
Publicado: (2020)

Correction: Antioxidant effect of nicotinamide mononucleotide in tendinopathy
por: Yamaura, Kohei, et al.
Publicado: (2022)

Fenofibrate exerts protective effects against gentamicin-induced toxicity in cochlear hair cells by activating antioxidant enzymes
por: Park, Channy, et al.
Publicado: (2017)

SIRT1 selectively exerts the metabolic protective effects of hepatocyte nicotinamide phosphoribosyltransferase
por: Higgins, Cassandra B., et al.
Publicado: (2022)

Phenolic Profile, Antioxidant, and Antidiabetic Potential Exerted by Millet Grain Varieties
por: Ofosu, Fred Kwame, et al.
Publicado: (2020)

Nicotinamide enhances osteoblast differentiation through activation of the mitochondrial antioxidant defense system
por: Yoon, Heein, et al.
Publicado: (2023)

Nicotinamide phosphoribosyltransferase regulates the cell differentiation and mineralization in cultured odontoblasts
por: Kang, Kyeong-Rok, et al.
Publicado: (2022)

Nicotinamide Phosphoribosyltransferase as a Key Molecule of the Aging/Senescence Process
por: Khaidizar, Fiqri D., et al.
Publicado: (2021)

Creatine and Nicotinamide Prevent Oxidant-Induced Senescence in Human Fibroblasts
por: Mahajan, Avinash S., et al.
Publicado: (2021)

Enhancement of Replication and Differentiation Potential of Human Bone Marrow Stem Cells by Nicotinamide Treatment
por: Ok, Jeong Su, et al.
Publicado: (2018)

Extracellular Nicotinamide Phosphoribosyltransferase Is a Component of the Senescence-Associated Secretory Phenotype
por: Kuehnemann, Chisaka, et al.
Publicado: (2022)

Inhibition of EZH2 exerts antitumorigenic effects in renal cell carcinoma via LATS1
por: Hong, Seong Hwi, et al.
Publicado: (2023)

Mimic of the Cellular Antioxidant Defense System for a Sustainable Regeneration of Nicotinamide Adenine Dinucleotide (NAD)
por: Jo, Seong-Min, et al.
Publicado: (2020)

Nicotinamide Mononucleotide and Coenzyme Q10 Protects Fibroblast Senescence Induced by Particulate Matter Preconditioned Mast Cells
por: Chang, Tsong-Min, et al.
Publicado: (2022)

Nicotinamide riboside exerts protective effect against aging-induced NAFLD-like hepatic dysfunction in mice
por: Han, Xue, et al.
Publicado: (2019)

Dezocine, An Opioid Analgesic, Exerts Antitumor Effects in Triple-Negative Breast Cancer by Targeting Nicotinamide Phosphoribosyltransferase
por: Xue, Chenyang, et al.
Publicado: (2021)

Nicotinamide Mononucleotide Ameliorates Cellular Senescence and Inflammation Caused by Sodium Iodate in RPE
por: Ren, Chengda, et al.
Publicado: (2022)

High-Dose Nicotinamide Suppresses ROS Generation and Augments Population Expansion during CD8(+) T Cell Activation
por: Choi, Ho Jin, et al.
Publicado: (2015)

Dehydrozingerone exerts beneficial metabolic effects in high-fat diet-induced obese mice viaAMPK activation in skeletal muscle
por: Kim, Su Jin, et al.
Publicado: (2015)

Proton Pump Inhibitors Exert Anti-Allergic Effects by Reducing TCTP Secretion
por: Choi, Sunghee, et al.
Publicado: (2009)

AICAR and nicotinamide treatment synergistically augment the proliferation and attenuate senescence-associated changes in mesenchymal stromal cells
por: Khorraminejad-Shirazi, Mohammadhossein, et al.
Publicado: (2020)

Links between accelerated replicative cellular senescence and down-regulation of SPHK1 transcription
por: Kim, Min Kyung, et al.
Publicado: (2019)

Rutin Exerts Cytotoxic and Senescence-Inducing Properties in Human Melanoma Cells
por: Pinzaru, Iulia, et al.
Publicado: (2021)

Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells
por: Fletcher, Rachel S., et al.
Publicado: (2017)

Modulation of Mitochondrial Membrane Potential and ROS Generation by Nicotinamide in a Manner Independent of SIRT1 and Mitophagy
por: Song, Seon Beom, et al.
Publicado: (2017)

Antioxidant effects of selenocysteine on replicative senescence in human adipose-derived mesenchymal stem cells
por: Suh, Nayoung, et al.
Publicado: (2017)

Involvement of Klotho, TNF-α and ADAMs in radiation-induced senescence of renal epithelial cells
por: Kim, Da Yeon, et al.
Publicado: (2021)

Phloretin Exerts Anti-Tuberculosis Activity and Suppresses Lung Inflammation
por: Jeon, Dasom, et al.
Publicado: (2017)

Ozonated Sunflower Oil Exerted Protective Effect for Embryo and Cell Survival via Potent Reduction Power and Antioxidant Activity in HDL with Strong Antimicrobial Activity
por: Cho, Kyung-Hyun, et al.
Publicado: (2021)

Nicotinamide phosphoribosyltransferase postpones rat bone marrow mesenchymal stem cell senescence by mediating NAD(+)–Sirt1 signaling
por: Pi, Chenchen, et al.
Publicado: (2019)

Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis
por: Moon, Seungtae, et al.
Publicado: (2018)

Nicotinamide Mononucleotide Attenuates Renal Interstitial Fibrosis After AKI by Suppressing Tubular DNA Damage and Senescence
por: Jia, Yan, et al.
Publicado: (2021)

NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells
por: Ratajczak, Joanna, et al.
Publicado: (2016)

CpG-DNA exerts antibacterial effects by protecting immune cells and producing bacteria-reactive antibodies
por: Kim, Te Ha, et al.
Publicado: (2018)

Antioxidant effect of pomegranate against streptozotocin-nicotinamide generated oxidative stress induced diabetic rats
por: Aboonabi, Anahita, et al.
Publicado: (2014)

Catechol-Type Flavonoids from the Branches of Elaeagnus glabra f. oxyphylla Exert Antioxidant Activity and an Inhibitory Effect on Amyloid-β Aggregation
por: Kim, Yu Jin, et al.
Publicado: (2020)

Polydeoxyribonucleotide exerts opposing effects on ERK activity in human skin keratinocytes and fibroblasts
por: Shin, Sun Mee, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_guso3vj5seg4kvuod6ruvlcouu