Brca2 Deficiency Leads to T Cell Loss and Immune Dysfunction

Germline mutations in the breast cancer type 2 susceptibility gene (BRCA2) are linked to familial breast cancer and the progressive bone marrow failure syndrome Fanconi anaemia. Established Brca2 mouse knockout models show embryonic lethality, but those with a truncating mutation at the C-terminus s...

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Detalles Bibliográficos
Autores principales: Jeong, Jun-hyeon, Jo, Areum, Park, Pilgu, Lee, Hyunsook, Lee, Hae-Ock
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363725/
https://www.ncbi.nlm.nih.gov/pubmed/25666348
http://dx.doi.org/10.14348/molcells.2015.2302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363725/
https://www.ncbi.nlm.nih.gov/pubmed/25666348
http://dx.doi.org/10.14348/molcells.2015.2302

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