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Co-Infection with Mycobacterium tuberculosis Impairs HIV-Specific CD8+ and CD4+ T Cell Functionality
The ability of antigen-specific T cells to simultaneously produce multiple cytokines is thought to correlate with the functional capacity and efficacy of T cells. These ‘polyfunctional’ T cells have been associated with control of HIV. We aimed to assess the impact of co-infection with Mycobacterium...
Autores principales: | Chetty, Shivan, Govender, Pamla, Zupkosky, Jennifer, Pillay, Mona, Ghebremichael, Musie, Moosa, Mahomed-Yunus S., Ndung’u, Thumbi, Porichis, Filippos, Kasprowicz, Victoria O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363785/ https://www.ncbi.nlm.nih.gov/pubmed/25781898 http://dx.doi.org/10.1371/journal.pone.0118654 |
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