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Differentiation of human induced pluripotent stem cells to mature functional Purkinje neurons

It remains a challenge to differentiate human induced pluripotent stem cells (iPSCs) or embryonic stem (ES) cells to Purkinje cells. In this study, we derived iPSCs from human fibroblasts and directed the specification of iPSCs first to Purkinje progenitors, by adding Fgf2 and insulin to the embryoi...

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Detalles Bibliográficos
Autores principales:	Wang, Shuyan, Wang, Bin, Pan, Na, Fu, Linlin, Wang, Chaodong, Song, Gongru, An, Jing, Liu, Zhongfeng, Zhu, Wanwan, Guan, Yunqian, Xu, Zhi-Qing David, Chan, Piu, Chen, Zhiguo, Zhang, Y. Alex
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363833/ https://www.ncbi.nlm.nih.gov/pubmed/25782665 http://dx.doi.org/10.1038/srep09232

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