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Fat mass- and obesity-associated gene Fto affects the dietary response in mouse white adipose tissue

Common variants of human fat mass- and obesity-associated gene Fto have been linked with higher body mass index, but the biological explanation for the link has remained obscure. Recent findings suggest that these variants affect the homeobox protein IRX3. Here we report that FTO has a role in white...

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Detalles Bibliográficos
Autores principales: Ronkainen, Justiina, Huusko, Tuija J., Soininen, Raija, Mondini, Eleonora, Cinti, Francesca, Mäkelä, Kari A., Kovalainen, Miia, Herzig, Karl-Heinz, Järvelin, Marjo-Riitta, Sebert, Sylvain, Savolainen, Markku J., Salonurmi, Tuire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363842/
https://www.ncbi.nlm.nih.gov/pubmed/25782772
http://dx.doi.org/10.1038/srep09233