Cargando…

Fat mass- and obesity-associated gene Fto affects the dietary response in mouse white adipose tissue

Common variants of human fat mass- and obesity-associated gene Fto have been linked with higher body mass index, but the biological explanation for the link has remained obscure. Recent findings suggest that these variants affect the homeobox protein IRX3. Here we report that FTO has a role in white...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ronkainen, Justiina, Huusko, Tuija J., Soininen, Raija, Mondini, Eleonora, Cinti, Francesca, Mäkelä, Kari A., Kovalainen, Miia, Herzig, Karl-Heinz, Järvelin, Marjo-Riitta, Sebert, Sylvain, Savolainen, Markku J., Salonurmi, Tuire
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363842/ https://www.ncbi.nlm.nih.gov/pubmed/25782772 http://dx.doi.org/10.1038/srep09233

Ejemplares similares

Fto-Deficiency Affects the Gene and MicroRNA Expression Involved in Brown Adipogenesis and Browning of White Adipose Tissue in Mice
por: Ronkainen, Justiina, et al.
Publicado: (2016)

The relationship of life-course patterns of adiposity with type 2 diabetes, depression, and their comorbidity in the Northern Finland Birth Cohort 1966
por: Choudhary, Priyanka, et al.
Publicado: (2022)

Long Telomeres in Blood Leukocytes Are Associated with a High Risk of Ascending Aortic Aneurysm
por: Huusko, Tuija J., et al.
Publicado: (2012)

4β-Hydroxycholesterol Signals From the Liver to Regulate Peripheral Cholesterol Transporters
por: Salonurmi, Tuire, et al.
Publicado: (2020)

The effects of group and single housing and automated animal monitoring on urinary corticosterone levels in male C57BL/6 mice
por: Kamakura, Remi, et al.
Publicado: (2016)

Influence of Farm Environment on Asthma during the Life Course: A Population-Based Birth Cohort Study in Northern Finland
por: Kantomaa, Marko T., et al.
Publicado: (2023)

Distinct Fatty Acid Compositions of HDL Phospholipids Are Characteristic of Metabolic Syndrome and Premature Coronary Heart Disease—Family Study
por: Paavola, Timo, et al.
Publicado: (2021)

Vitamin D and the Promotion of Long-Term Metabolic Health from a Programming Perspective
por: Palaniswamy, Saranya, et al.
Publicado: (2016)

Interactions between macro-nutrients’ intake, FTO and IRX3 gene expression, and FTO genotype in obese and overweight male adolescents
por: Doaei, Saeid, et al.
Publicado: (2019)

Changes in FTO and IRX3 gene expression in obese and overweight male adolescents undergoing an intensive lifestyle intervention and the role of FTO genotype in this interaction
por: Doaei, Saeid, et al.
Publicado: (2019)

Vitamin D Status and Components of Metabolic Syndrome in Older Subjects from Northern Finland (Latitude 65°North)
por: Mutt, Shivaprakash Jagalur, et al.
Publicado: (2019)

Elevated Levels of Plasma IgA Autoantibodies against Oxidized LDL Found in Proliferative Diabetic Retinopathy but Not in Nonproliferative Retinopathy
por: Vavuli, Satu, et al.
Publicado: (2016)

The Role of FTO Genotype in the Association Between FTO Gene Expression and Anthropometric Measures in Obese and Overweight Adolescent Boys
por: Doaei, Saeid, et al.
Publicado: (2018)

Work-related stress and well-being in association with epigenetic age acceleration: A Northern Finland Birth Cohort 1966 Study
por: Freni-Sterrantino, Anna, et al.
Publicado: (2022)

Vitamin D Levels in Women with Polycystic Ovary Syndrome: A Population-Based Study
por: Lumme, Johanna, et al.
Publicado: (2019)

Genetic fine-mapping from summary data using a nonlocal prior improves the detection of multiple causal variants
por: Karhunen, Ville, et al.
Publicado: (2023)

Vitamin D Status in Women with a History of Infertility and Decreased Fecundability: A Population-Based Study
por: Lumme, Johanna, et al.
Publicado: (2023)

The association between physical fitness and depressive symptoms among young adults: results of the Northern Finland 1966 birth cohort study
por: Suija, Kadri, et al.
Publicado: (2013)

Low eating self-efficacy is associated with unfavorable eating behavior tendencies among individuals with overweight and obesity
por: Oikarinen, Noora, et al.
Publicado: (2023)

Potential determinants of vitamin D in Finnish adults: a cross-sectional study from the Northern Finland birth cohort 1966
por: Palaniswamy, Saranya, et al.
Publicado: (2017)

Impaired HDL2-mediated cholesterol efflux is associated with metabolic syndrome in families with early onset coronary heart disease and low HDL-cholesterol level
por: Paavola, Timo, et al.
Publicado: (2017)

Effect of common pregnancy and perinatal complications on offspring metabolic traits across the life course: a multi-cohort study
por: Elhakeem, Ahmed, et al.
Publicado: (2023)

The Association of Genotype-Based Inbreeding Coefficient with a Range of Physical and Psychological Human Traits
por: Verweij, Karin J. H., et al.
Publicado: (2014)

Life-Course Analysis of a Fat Mass and Obesity-Associated (FTO) Gene Variant and Body Mass Index in the Northern Finland Birth Cohort 1966 Using Structural Equation Modeling
por: Kaakinen, Marika, et al.
Publicado: (2010)

A haplotype of three SNPs in FTO had a strong association with body composition and BMI in Iranian male adolescents
por: Kalantari, Naser, et al.
Publicado: (2018)

PCSK9 Levels and Metabolic Profiles in Elderly Subjects with Different Glucose Tolerance under Statin Therapy
por: Mäkelä, Kari A., et al.
Publicado: (2021)

The determinants and longitudinal changes in vitamin D status in middle-age: a Northern Finland Birth Cohort 1966 study
por: Ikonen, Helmi, et al.
Publicado: (2021)

Metabolic Signatures of Insulin Resistance in 7,098 Young Adults
por: Würtz, Peter, et al.
Publicado: (2012)

Up-regulation of FTO gene expression was associated with increase in skeletal muscle mass in overweight male adolescents
por: Doaei, Saeid, et al.
Publicado: (2019)

Lifestyle counselling by persuasive information and communications technology reduces prevalence of metabolic syndrome in a dose–response manner: a randomized clinical trial (PrevMetSyn)
por: Seo, Young-Gyun, et al.
Publicado: (2020)

A complete linkage disequilibrium in a haplotype of three SNPs in Fat Mass and Obesity associated (FTO) gene was strongly associated with anthropometric indices after controlling for calorie intake and physical activity
por: Kalantari, Naser, et al.
Publicado: (2018)

25-Hydroxyvitamin D Concentration and Leukocyte Telomere Length in Young Adults: Findings From the Northern Finland Birth Cohort 1966
por: Williams, Dylan M., et al.
Publicado: (2016)

Polycystic ovary syndrome and leukocyte telomere length: cross-sectional and longitudinal changes
por: Pölönen, Johanna, et al.
Publicado: (2022)

Meal Frequencies Modify the Effect of Common Genetic Variants on Body Mass Index in Adolescents of the Northern Finland Birth Cohort 1986
por: Jääskeläinen, Anne, et al.
Publicado: (2013)

An optimal growth pattern during pregnancy and early childhood associates with better fertility in men
por: Laru, Johanna, et al.
Publicado: (2022)

Understanding the complexity of glycaemic health: systematic bio-psychosocial modelling of fasting glucose in middle-age adults; a DynaHEALTH study
por: Lowry, Estelle, et al.
Publicado: (2018)

Genetic correlation and causal relationships between cardio-metabolic traits and lung function impairment
por: Wielscher, Matthias, et al.
Publicado: (2021)

Colonic Delivery of Nutrients for Sustained and Prolonged Release of Gut Peptides: A Novel Strategy for Appetite Management
por: Kamakura, Remi, et al.
Publicado: (2022)

The Interplay of Variants Near LEKR and CCNL1 and Social Stress in Relation to Birth Size
por: Ali Khan, Anokhi, et al.
Publicado: (2012)

Cohort Profile: 46 years of follow-up of the Northern Finland Birth Cohort 1966 (NFBC1966)
por: Nordström, Tanja, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_8e48arbl0bstb0nkrqhvq5orcf