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Hepatoprotective Effect of Silymarin (Silybum marianum) on Hepatotoxicity Induced by Acetaminophen in Spontaneously Hypertensive Rats

This study was aimed to investigate the effect of Silymarin (SLM) on the hypertension state and the liver function changes induced by acetaminophen (APAP) in spontaneously hypertensive rat (SHR). Animals normotensive (N) or hypertensive (SHR) were treated or not with APAP (3 g/kg, oral) or previousl...

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Detalles Bibliográficos
Autores principales:	Freitag, Abel Felipe, Cardia, Gabriel Fernando Esteves, da Rocha, Bruno Ambrósio, Aguiar, Rafael Pazzinatto, Silva-Comar, Francielli Maria de Souza, Spironello, Ricardo Alexandre, Grespan, Renata, Caparroz-Assef, Silvana Martins, Bersani-Amado, Ciomar Aparecida, Cuman, Roberto Kenji Nakamura
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363982/ https://www.ncbi.nlm.nih.gov/pubmed/25821491 http://dx.doi.org/10.1155/2015/538317

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