Functional Analysis of Sirtuin Genes in Multiple Plasmodium falciparum Strains

Plasmodium falciparum, the causative agent of severe human malaria, employs antigenic variation to avoid host immunity. Antigenic variation is achieved by transcriptional switching amongst polymorphic var genes, enforced by epigenetic modification of chromatin. The histone-modifying ‘sirtuin’ enzyme...

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Detalles Bibliográficos
Autores principales: Merrick, Catherine J., Jiang, Rays H. Y., Skillman, Kristen M., Samarakoon, Upeka, Moore, Rachel M., Dzikowski, Ron, Ferdig, Michael T., Duraisingh, Manoj T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364008/
https://www.ncbi.nlm.nih.gov/pubmed/25780929
http://dx.doi.org/10.1371/journal.pone.0118865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364008/
https://www.ncbi.nlm.nih.gov/pubmed/25780929
http://dx.doi.org/10.1371/journal.pone.0118865

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