Cargando…

Dementia trials and dementia tribulations: methodological and analytical challenges in dementia research

Dementia is a substantial and increasing public health concern. Despite decades of research, a cure or effective preventative treatment for dementia remains elusive. We offer critical review of contemporary dementia research and discuss potential reasons why progress in the field has not been as rap...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ritchie, Craig W, Terrera, Graciela Muniz, Quinn, Terence J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364079/ https://www.ncbi.nlm.nih.gov/pubmed/25788988 http://dx.doi.org/10.1186/s13195-015-0113-6

Ejemplares similares

Assessing individual-level change in dementia research: a review of methodologies
por: Murray, Aja Louise, et al.
Publicado: (2021)

Application of Big Data and Artificial Intelligence technologies to dementia prevention research: an opportunity for low-and-middle-income countries
por: Danso, Samuel O, et al.
Publicado: (2019)

Understanding and predicting the longitudinal course of dementia
por: Melis, René J.F., et al.
Publicado: (2019)

Associations between cerebrospinal fluid markers and cognition in ageing and dementia: A systematic review
por: Saunders, Tyler S., et al.
Publicado: (2022)

Virtual Cohorts and Synthetic Data in Dementia: An Illustration of Their Potential to Advance Research
por: Muniz-Terrera, Graciela, et al.
Publicado: (2021)

Inherited risk of dementia and the progression of cerebral small vessel disease and inflammatory markers in cognitively healthy midlife adults: the PREVENT-Dementia study
por: Low, Audrey, et al.
Publicado: (2021)

Developing an Explainable Machine Learning-Based Personalised Dementia Risk Prediction Model: A Transfer Learning Approach With Ensemble Learning Algorithms
por: Danso, Samuel O., et al.
Publicado: (2021)

Self‐reported diabetes is associated with allocentric spatial processing in the European Prevention of Alzheimer's Dementia Longitudinal Cohort Study
por: Gregory, Sarah, et al.
Publicado: (2022)

Macrostructural brain alterations at midlife are connected to cardiovascular and not inherited risk of future dementia: the PREVENT-Dementia study
por: Dounavi, Maria-Eleni, et al.
Publicado: (2022)

Associations between midlife chronic conditions and medication use with anxiety and depression: A cross-sectional analysis of the PREVENT Dementia study
por: Stirland, Lucy E, et al.
Publicado: (2020)

Association between anticholinergic burden and dementia in UK Biobank
por: Mur, Jure, et al.
Publicado: (2021)

Interactions between apolipoprotein E, sex, and amyloid-beta on cerebrospinal fluid p-tau levels in the European prevention of Alzheimer's dementia longitudinal cohort study (EPAD LCS)
por: Saunders, Tyler S., et al.
Publicado: (2022)

Statistical methods for dementia risk prediction and recommendations for future work: A systematic review
por: Goerdten, Jantje, et al.
Publicado: (2019)

Association between anticholinergic burden and dementia in UK Biobank
por: Mur, Jure, et al.
Publicado: (2022)

Evidence of cerebral hemodynamic dysregulation in middle-aged APOE ε4 carriers: The PREVENT-Dementia study
por: Dounavi, Maria-Eleni, et al.
Publicado: (2021)

Comparison of Cox proportional hazards regression and generalized Cox regression models applied in dementia risk prediction
por: Goerdten, Jantje, et al.
Publicado: (2020)

Multidomain trials to prevent dementia: addressing methodological challenges
por: Montero-Odasso, Manuel, et al.
Publicado: (2022)

Differences in the longitudinal change of behaviours related to dementia in long-term care: a growth mixture modelling approach
por: Robitaille, Annie, et al.
Publicado: (2023)

Duration of Reproductive Period and Risk of Transitioning to Mild Cognitive Impairment and Dementia
por: Yoneda, Tomiko, et al.
Publicado: (2021)

Duration of Reproductive Period and Risk of Transitioning to Mild Cognitive Impairment and Dementia
por: Knight, Jamie, et al.
Publicado: (2021)

Challenges of anticipation of future decisions in dementia and dementia research
por: Perry, Julia
Publicado: (2022)

Comparing international dementia research priorities—Systematic review
por: Logan, Monica, et al.
Publicado: (2022)

What matters to people with memory problems, healthy volunteers and health and social care professionals in the context of developing treatment to prevent Alzheimer's dementia? A qualitative study
por: Watson, Julie, et al.
Publicado: (2019)

Modifiable and non-modifiable risk factors of dementia on midlife cerebral small vessel disease in cognitively healthy middle-aged adults: the PREVENT-Dementia study
por: Low, Audrey, et al.
Publicado: (2022)

Variation in VKORC1 Is Associated with Vascular Dementia
por: Mur, Jure, et al.
Publicado: (2021)

Guidelines for reporting methodological challenges and evaluating potential bias in dementia research
por: Weuve, Jennifer, et al.
Publicado: (2015)

METHODOLOGICAL STRATEGIES AND CHALLENGES FOR EVALUATING PARTICIPANT VIEWS ON DEMENTIA RESEARCH RECRUITMENT
por: Block, Laura, et al.
Publicado: (2019)

Tackling dementia globally: the Global Dementia Prevention Program (GloDePP) collaboration
por: Chan, Kit Yee, et al.
Publicado: (2019)

COVID-19: challenges for dementia care and research
por: Dourado, Marcia Cristina Nascimento, et al.
Publicado: (2020)

Fibrolase: Trials and Tribulations
por: Markland, Francis S., et al.
Publicado: (2010)

Cognitive Dispersion Predicts Grip Strength Trajectories in Men but not Women in a Sample of the Oldest Old Without Dementia
por: Watermeyer, Tamlyn, et al.
Publicado: (2021)

Motoric Cognitive Risk Syndrome: Its prognostic value for dementia and other health outcomes. A systematic review
por: Mullin, Donncha, et al.
Publicado: (2021)

Motoric Cognitive Risk Syndrome: Its prognostic value for dementia and other health outcomes. A systematic review
por: Mullin, Donncha, et al.
Publicado: (2021)

A Perspective: Challenges in Dementia Research
por: Stecker, Mark
Publicado: (2022)

Research in Dementia Praecox
por: Macleod, Neil
Publicado: (1937)

Challenges of Dementia Care in China
por: Chen, Zheng, et al.
Publicado: (2017)

CAIDE dementia risk score relates to severity and progression of cerebral small vessel disease in healthy midlife adults: the PREVENT-Dementia study
por: Low, Audrey, et al.
Publicado: (2022)

Dementia Research on Facebook and Twitter: Current Practice and Challenges
por: Hrincu, Viorica, et al.
Publicado: (2022)

Hormonal contraception and risk for cognitive impairment or Alzheimer's disease and related dementias in young women: a scoping review of the evidence
por: Gregory, Sarah, et al.
Publicado: (2023)

Challenges in the diagnosis of dementia: insights from the United Kingdom-Brazil Dementia Workshop
por: Calil, Victor, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_fqkv23eu5g7j7l9bc1iu59el3c