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Inner ear hair cells deteriorate in mice engineered to have no or diminished innervation

The innervation of the inner ear critically depends on the two neurotrophins Ntf3 and Bdnf. In contrast to this molecularly well-established dependency, evidence regarding the need of innervation for long-term maintenance of inner ear hair cells is inconclusive, due to experimental variability. Muta...

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Detalles Bibliográficos
Autores principales:	Kersigo, Jennifer, Fritzsch, Bernd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364252/ https://www.ncbi.nlm.nih.gov/pubmed/25852547 http://dx.doi.org/10.3389/fnagi.2015.00033

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