Enhanced endogenous bone morphogenetic protein signaling protects against bleomycin induced pulmonary fibrosis

BACKGROUND: Effective treatments for fibrotic diseases such as idiopathic pulmonary fibrosis are largely lacking. Transforming growth factor beta (TGFβ) plays a central role in the pathophysiology of fibrosis. We hypothesized that bone morphogenetic proteins (BMP), another family within the TGFβ sup...

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Detalles Bibliográficos
Autores principales: De Langhe, Ellen, Cailotto, Frederic, De Vooght, Vanessa, Aznar-Lopez, Carolina, Vanoirbeek, Jeroen Alfons, Luyten, Frank Prosper, Lories, Rik Jozef Urbain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364322/
https://www.ncbi.nlm.nih.gov/pubmed/25849157
http://dx.doi.org/10.1186/s12931-015-0202-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364322/
https://www.ncbi.nlm.nih.gov/pubmed/25849157
http://dx.doi.org/10.1186/s12931-015-0202-x

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