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Enhanced endogenous bone morphogenetic protein signaling protects against bleomycin induced pulmonary fibrosis

BACKGROUND: Effective treatments for fibrotic diseases such as idiopathic pulmonary fibrosis are largely lacking. Transforming growth factor beta (TGFβ) plays a central role in the pathophysiology of fibrosis. We hypothesized that bone morphogenetic proteins (BMP), another family within the TGFβ sup...

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Detalles Bibliográficos
Autores principales:	De Langhe, Ellen, Cailotto, Frederic, De Vooght, Vanessa, Aznar-Lopez, Carolina, Vanoirbeek, Jeroen Alfons, Luyten, Frank Prosper, Lories, Rik Jozef Urbain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364322/ https://www.ncbi.nlm.nih.gov/pubmed/25849157 http://dx.doi.org/10.1186/s12931-015-0202-x

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