DUX4 promotes transcription of FRG2 by directly activating its promoter in facioscapulohumeral muscular dystrophy

BACKGROUND: The most common form of facioscapulohumeral muscular dystrophy (FSHD) is caused by a genetic contraction of the polymorphic D4Z4 macrosatellite repeat array in the subtelomeric region of chromosome 4q. In some studies, genes centromeric to the D4Z4 repeat array have been reported to be o...

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Detalles Bibliográficos
Autores principales: Thijssen, Peter E, Balog, Judit, Yao, Zizhen, Pham, Tan Phát, Tawil, Rabi, Tapscott, Stephen J, Van der Maarel, Silvère M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364343/
https://www.ncbi.nlm.nih.gov/pubmed/25789155
http://dx.doi.org/10.1186/2044-5040-4-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364343/
https://www.ncbi.nlm.nih.gov/pubmed/25789155
http://dx.doi.org/10.1186/2044-5040-4-19

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