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Associations of neighborhood area level deprivation with the metabolic syndrome and inflammation among middle- and older- age adults

BACKGROUND: The study examines the association of neighborhood socioeconomic deprivation and metabolic syndrome with inflammation. METHODS: The analysis included 19, 079 black and white participants from the REasons for Geographic And Racial Differences in Stroke Study who were age > 45 years at...

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Autores principales: Keita, Akilah Dulin, Judd, Suzanne E, Howard, Virginia J, Carson, April P, Ard, Jamy D, Fernandez, Jose R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364504/
https://www.ncbi.nlm.nih.gov/pubmed/25539758
http://dx.doi.org/10.1186/1471-2458-14-1319
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author Keita, Akilah Dulin
Judd, Suzanne E
Howard, Virginia J
Carson, April P
Ard, Jamy D
Fernandez, Jose R
author_facet Keita, Akilah Dulin
Judd, Suzanne E
Howard, Virginia J
Carson, April P
Ard, Jamy D
Fernandez, Jose R
author_sort Keita, Akilah Dulin
collection PubMed
description BACKGROUND: The study examines the association of neighborhood socioeconomic deprivation and metabolic syndrome with inflammation. METHODS: The analysis included 19, 079 black and white participants from the REasons for Geographic And Racial Differences in Stroke Study who were age > 45 years at baseline. Logistic regression examined whether neighborhood deprivation was associated with increased odds of METS and CRP-MetS. RESULTS: Among black adults, residing in the most deprived neighborhoods was associated with increased odds of obesity (p < .01), lower HDL (p < .001), high blood pressure (p < .01), elevated fasting glucose (p < .001), inflammation (p < .01), and CRP-MetS (p < .001). Among white adults, neighborhood deprivation was associated with higher waist circumference (p < .001), lower HDL (p < .001), higher triglycerides (p < .01), higher glucose (p < .001), higher BMI (p < .0001), higher blood pressure (p = .01), METS (p < .001), inflammation (p < .01) and CRP-MetS (p < .001). CONCLUSIONS: These findings highlight the role of neighborhood socioeconomic deprivation on METS and CRP-MetS for black and white adults. Interventions tailored to address the contextual effects of deprived neighborhoods may reduce the observed neighborhood disparities. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/1471-2458-14-1319) contains supplementary material, which is available to authorized users.
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spelling pubmed-43645042015-03-19 Associations of neighborhood area level deprivation with the metabolic syndrome and inflammation among middle- and older- age adults Keita, Akilah Dulin Judd, Suzanne E Howard, Virginia J Carson, April P Ard, Jamy D Fernandez, Jose R BMC Public Health Research Article BACKGROUND: The study examines the association of neighborhood socioeconomic deprivation and metabolic syndrome with inflammation. METHODS: The analysis included 19, 079 black and white participants from the REasons for Geographic And Racial Differences in Stroke Study who were age > 45 years at baseline. Logistic regression examined whether neighborhood deprivation was associated with increased odds of METS and CRP-MetS. RESULTS: Among black adults, residing in the most deprived neighborhoods was associated with increased odds of obesity (p < .01), lower HDL (p < .001), high blood pressure (p < .01), elevated fasting glucose (p < .001), inflammation (p < .01), and CRP-MetS (p < .001). Among white adults, neighborhood deprivation was associated with higher waist circumference (p < .001), lower HDL (p < .001), higher triglycerides (p < .01), higher glucose (p < .001), higher BMI (p < .0001), higher blood pressure (p = .01), METS (p < .001), inflammation (p < .01) and CRP-MetS (p < .001). CONCLUSIONS: These findings highlight the role of neighborhood socioeconomic deprivation on METS and CRP-MetS for black and white adults. Interventions tailored to address the contextual effects of deprived neighborhoods may reduce the observed neighborhood disparities. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/1471-2458-14-1319) contains supplementary material, which is available to authorized users. BioMed Central 2014-12-23 /pmc/articles/PMC4364504/ /pubmed/25539758 http://dx.doi.org/10.1186/1471-2458-14-1319 Text en © Keita et al.; licensee BioMed Central. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Keita, Akilah Dulin
Judd, Suzanne E
Howard, Virginia J
Carson, April P
Ard, Jamy D
Fernandez, Jose R
Associations of neighborhood area level deprivation with the metabolic syndrome and inflammation among middle- and older- age adults
title Associations of neighborhood area level deprivation with the metabolic syndrome and inflammation among middle- and older- age adults
title_full Associations of neighborhood area level deprivation with the metabolic syndrome and inflammation among middle- and older- age adults
title_fullStr Associations of neighborhood area level deprivation with the metabolic syndrome and inflammation among middle- and older- age adults
title_full_unstemmed Associations of neighborhood area level deprivation with the metabolic syndrome and inflammation among middle- and older- age adults
title_short Associations of neighborhood area level deprivation with the metabolic syndrome and inflammation among middle- and older- age adults
title_sort associations of neighborhood area level deprivation with the metabolic syndrome and inflammation among middle- and older- age adults
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364504/
https://www.ncbi.nlm.nih.gov/pubmed/25539758
http://dx.doi.org/10.1186/1471-2458-14-1319
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