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Paclitaxel-induced neuropathy: potential association of MAPT and GSK3B genotypes

BACKGROUND: Paclitaxel treatment produces dose-limiting peripheral neurotoxicity, which adversely affects treatment and long-term outcomes. In the present study, the contribution of genetic polymorphisms to paclitaxel-induced neurotoxicity were assessed in 21 patients, focusing on polymorphisms invo...

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Detalles Bibliográficos
Autores principales: Park, Susanna B, Kwok, John B, Loy, Clement T, Friedlander, Michael L, Lin, Cindy S-Y, Krishnan, Arun V, Lewis, Craig R, Kiernan, Matthew C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364586/
https://www.ncbi.nlm.nih.gov/pubmed/25535399
http://dx.doi.org/10.1186/1471-2407-14-993

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