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Upregulation of Glycolytic Enzymes, Mitochondrial Dysfunction and Increased Cytotoxicity in Glial Cells Treated with Alzheimer’s Disease Plasma
Alzheimer’s disease (AD) is a neurodegenerative disorder associated with increased oxidative stress and neuroinflammation. Markers of increased protein, lipid and nucleic acid oxidation and reduced activities of antioxidant enzymes have been reported in AD plasma. Amyloid plaques in the AD brain eli...
Autores principales: | Jayasena, Tharusha, Poljak, Anne, Braidy, Nady, Smythe, George, Raftery, Mark, Hill, Mark, Brodaty, Henry, Trollor, Julian, Kochan, Nicole, Sachdev, Perminder |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364672/ https://www.ncbi.nlm.nih.gov/pubmed/25785936 http://dx.doi.org/10.1371/journal.pone.0116092 |
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