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Upregulation of Glycolytic Enzymes, Mitochondrial Dysfunction and Increased Cytotoxicity in Glial Cells Treated with Alzheimer’s Disease Plasma

Alzheimer’s disease (AD) is a neurodegenerative disorder associated with increased oxidative stress and neuroinflammation. Markers of increased protein, lipid and nucleic acid oxidation and reduced activities of antioxidant enzymes have been reported in AD plasma. Amyloid plaques in the AD brain eli...

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Detalles Bibliográficos
Autores principales: Jayasena, Tharusha, Poljak, Anne, Braidy, Nady, Smythe, George, Raftery, Mark, Hill, Mark, Brodaty, Henry, Trollor, Julian, Kochan, Nicole, Sachdev, Perminder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364672/
https://www.ncbi.nlm.nih.gov/pubmed/25785936
http://dx.doi.org/10.1371/journal.pone.0116092

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