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Novel Genetic Locus Implicated for HIV-1 Acquisition with Putative Regulatory Links to HIV Replication and Infectivity: A Genome-Wide Association Study
Fifty percent of variability in HIV-1 susceptibility is attributable to host genetics. Thus identifying genetic associations is essential to understanding pathogenesis of HIV-1 and important for targeting drug development. To date, however, CCR5 remains the only gene conclusively associated with HIV...
Autores principales: | Johnson, Eric O., Hancock, Dana B., Gaddis, Nathan C., Levy, Joshua L., Page, Grier, Novak, Scott P., Glasheen, Cristie, Saccone, Nancy L., Rice, John P., Moreau, Michael P., Doheny, Kimberly F., Romm, Jane M., Brooks, Andrew I., Aouizerat, Bradley E., Bierut, Laura J., Kral, Alex H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364715/ https://www.ncbi.nlm.nih.gov/pubmed/25786224 http://dx.doi.org/10.1371/journal.pone.0118149 |
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