A Novel Class of Mitochondria-Targeted Soft Electrophiles Modifies Mitochondrial Proteins and Inhibits Mitochondrial Metabolism in Breast Cancer Cells through Redox Mechanisms

Despite advances in screening and treatment over the past several years, breast cancer remains a leading cause of cancer-related death among women in the United States. A major goal in breast cancer treatment is to develop safe and clinically useful therapeutic agents that will prevent the recurrenc...

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Detalles Bibliográficos
Autores principales: Vayalil, Praveen K., Oh, Joo-Yeun, Zhou, Fen, Diers, Anne R., Smith, M. Ryan, Golzarian, Hafez, Oliver, Patsy G., Smith, Robin A. J., Murphy, Michael P., Velu, Sadanandan E., Landar, Aimee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364723/
https://www.ncbi.nlm.nih.gov/pubmed/25785718
http://dx.doi.org/10.1371/journal.pone.0120460

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