Cargando…

A Newly Designed Curcumin Analog Y20 Mitigates Cardiac Injury via Anti-Inflammatory and Anti-Oxidant Actions in Obese Rats

Obesity is strongly associated with the cause of structural and functional changes of the heart in both human and animal models. Oxidative stress and inflammation play a critical role in the development of obesity-induced cardiac disorders. Curcumin is a natural product from Curcuma Longa with multi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qian, Yuanyuan, Zhong, Peng, Liang, Dandan, Xu, Zheng, Skibba, Melissa, Zeng, Chunlai, Li, Xiaokun, Wei, Tiemin, Wu, Lianpin, Liang, Guang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364772/ https://www.ncbi.nlm.nih.gov/pubmed/25786209 http://dx.doi.org/10.1371/journal.pone.0120215

Ejemplares similares

Anti-inflammatory effects of novel curcumin analogs in experimental acute lung injury
por: Zhang, Yali, et al.
Publicado: (2015)

Discovery and evaluation of asymmetrical monocarbonyl analogs of curcumin as anti-inflammatory agents
por: Zhang, Yali, et al.
Publicado: (2014)

Anti-Lung Cancer Activity of the Curcumin Analog JZ534 In Vitro
por: Wu, Jianzhang, et al.
Publicado: (2015)

Evaluation of a curcumin analog as an anti-cancer agent inducing ER stress-mediated apoptosis in non-small cell lung cancer cells
por: Liu, Zhiguo, et al.
Publicado: (2013)

Evaluating the Anti-cancer Efficacy of a Synthetic Curcumin Analog on Human Melanoma Cells and Its Interaction with Standard Chemotherapeutics
por: Parashar, Krishan, et al.
Publicado: (2019)

Synthesis and biological evaluation of a novel class of curcumin analogs as anti-inflammatory agents for prevention and treatment of sepsis in mouse model
por: Zhao, Chengguang, et al.
Publicado: (2015)

Anti-Metastatic and Anti-Angiogenic Effects of Curcumin Analog DK1 on Human Osteosarcoma Cells In Vitro
por: Aziz, Muhammad Nazirul Mubin, et al.
Publicado: (2021)

Synthesis and Cytotoxic Evaluation of Monocarbonyl Analogs of Curcumin as Potential Anti‐Tumor Agents
por: Pan, Zheer, et al.
Publicado: (2016)

Monocarbonyl Analogs of Curcumin Based on the Pseudopelletierine Scaffold: Synthesis and Anti-Inflammatory Activity
por: Pawelski, Damian, et al.
Publicado: (2021)

Novel EGFR inhibitors attenuate cardiac hypertrophy induced by angiotensin II
por: Peng, Kesong, et al.
Publicado: (2016)

Development of Epoxyeicosatrienoic Acid Analogs with in Vivo Anti-Hypertensive Actions
por: Imig, John D., et al.
Publicado: (2010)

Dehydrozingerone, a Curcumin Analog, as a Potential Anti-Prostate Cancer Inhibitor In Vitro and In Vivo
por: Mapoung, Sariya, et al.
Publicado: (2020)

In vitro anti-Trypanosoma cruzi activity enhancement of curcumin by its monoketone tetramethoxy analog diveratralacetone
por: Souza, Julia M., et al.
Publicado: (2021)

Curcumin analog GO‐Y030 boosts the efficacy of anti‐PD‐1 cancer immunotherapy
por: MaruYama, Takashi, et al.
Publicado: (2021)

Curcumin Analogs Reduce Stress and Inflammation Indices in Experimental Models of Diabetes
por: Biswas, Saumik, et al.
Publicado: (2019)

Novel Chemically Modified Curcumin (CMC) Analogs Exhibit Anti-Melanogenic Activity in Primary Human Melanocytes
por: Goenka, Shilpi, et al.
Publicado: (2021)

Development of Stable Amino-Pyrimidine–Curcumin Analogs: Synthesis, Equilibria in Solution, and Potential Anti-Proliferative Activity
por: Mari, Matteo, et al.
Publicado: (2023)

Selective Targeting of Cancer Cells by Oxidative Vulnerabilities with Novel Curcumin Analogs
por: Pignanelli, Christopher, et al.
Publicado: (2017)

Anti-inflammatory Action of Curcumin and Its Use in the Treatment of Lifestyle-related Diseases
por: Shimizu, Kana, et al.
Publicado: (2019)

Curcumin Anti-Apoptotic Action in a Model of Intestinal Epithelial Inflammatory Damage
por: Loganes, Claudia, et al.
Publicado: (2017)

Dual Action of Curcumin as an Anti- and Pro-Oxidant from a Biophysical Perspective
por: Wolnicka-Glubisz, Agnieszka, et al.
Publicado: (2023)

Synthesis and Evaluation of a Series of Novel Asymmetrical Curcumin Analogs for the Treatment of Inflammation
por: Zhang, Yali, et al.
Publicado: (2014)

Discovery and evaluation of novel anti-inflammatory derivatives of natural bioactive curcumin
por: Zhang, Yali, et al.
Publicado: (2014)

Enhanced anti-hepatoma effect of a novel curcumin analog C086 via solid dispersion technology
por: Deng, Yanping, et al.
Publicado: (2020)

Curcumin analog B14 has high bioavailability and enhances the effect of anti‐breast cancer cells in vitro and in vivo
por: Shen, Hui, et al.
Publicado: (2020)

Inhibition of HIV-1 by curcumin A, a novel curcumin analog
por: Kumari, Namita, et al.
Publicado: (2015)

Targeting JNK by a New Curcumin Analog to Inhibit NF-kB-Mediated Expression of Cell Adhesion Molecules Attenuates Renal Macrophage Infiltration and Injury in Diabetic Mice
por: Pan, Yong, et al.
Publicado: (2013)

Curcumin: An age-old anti-inflammatory and anti-neoplastic agent
por: Fadus, Matthew C., et al.
Publicado: (2016)

The Beneficial Effects of Combining Anti-Aβ Antibody NP106 and Curcumin Analog TML-6 on the Treatment of Alzheimer’s Disease in APP/PS1 Mice
por: Su, Ih-Jen, et al.
Publicado: (2022)

Epoxyeicosatrienoic Acid Analog Decreases Renal Fibrosis by Reducing Epithelial-to-Mesenchymal Transition
por: Skibba, Melissa, et al.
Publicado: (2017)

Anti-Plasmodium activity of ceramide analogs
por: Labaied, Mehdi, et al.
Publicado: (2004)

Inhibition Of JNK Phosphorylation By Curcumin Analog C66 Protects LPS-Induced Acute Lung Injury
por: Xiao, Zhongxiang, et al.
Publicado: (2019)

In Vivo and In Vitro Suppression of Hepatocellular Carcinoma by EF24, a Curcumin Analog
por: Liu, Haitao, et al.
Publicado: (2012)

Antiproliferative effects of curcumin analog L49H37 in pancreatic stellate cells: a comparative study
por: Gundewar, Chinmay, et al.
Publicado: (2015)

Synthesis and Evaluation of the Anti-Oxidant Capacity of Curcumin Glucuronides, the Major Curcumin Metabolites
por: Choudhury, Ambar K., et al.
Publicado: (2015)

Resveratrol: Anti-Obesity Mechanisms of Action
por: Aguirre, Leixuri, et al.
Publicado: (2014)

Anti-inflammatory Effects of Curcumin in Microglial Cells
por: Yu, Yangyang, et al.
Publicado: (2018)

Anti-infective Properties of the Golden Spice Curcumin
por: Praditya, Dimas, et al.
Publicado: (2019)

Curcumin AntiCancer Studies in Pancreatic Cancer
por: Bimonte, Sabrina, et al.
Publicado: (2016)

Effect of curcumin analogs onα-synuclein aggregation and cytotoxicity
por: Jha, Narendra Nath, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_546ljhf2qi7mskv8k7eccv79iv