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Differential Subcellular Localization Renders HAI-2 a Matriptase Inhibitor in Breast Cancer Cells but Not in Mammary Epithelial Cells

The type 2 transmembrane serine protease matriptase is under tight control primarily by the actions of the integral membrane Kunitz-type serine protease inhibitor HAI-1. Growing evidence indicates that HAI-2 might also be involved in matriptase inhibition in some contexts. Here we showed that matrip...

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Detalles Bibliográficos
Autores principales: Chang, Hsiang-Hua D., Xu, Yuan, Lai, Hongyu, Yang, Xiaoyu, Tseng, Chun-Che, Lai, Ying-Jung J., Pan, Yu, Zhou, Emily, Johnson, Michael D., Wang, Jehng-Kang, Lin, Chen-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364774/
https://www.ncbi.nlm.nih.gov/pubmed/25786220
http://dx.doi.org/10.1371/journal.pone.0120489