Cargando…
Differential Subcellular Localization Renders HAI-2 a Matriptase Inhibitor in Breast Cancer Cells but Not in Mammary Epithelial Cells
The type 2 transmembrane serine protease matriptase is under tight control primarily by the actions of the integral membrane Kunitz-type serine protease inhibitor HAI-1. Growing evidence indicates that HAI-2 might also be involved in matriptase inhibition in some contexts. Here we showed that matrip...
Autores principales: | Chang, Hsiang-Hua D., Xu, Yuan, Lai, Hongyu, Yang, Xiaoyu, Tseng, Chun-Che, Lai, Ying-Jung J., Pan, Yu, Zhou, Emily, Johnson, Michael D., Wang, Jehng-Kang, Lin, Chen-Yong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364774/ https://www.ncbi.nlm.nih.gov/pubmed/25786220 http://dx.doi.org/10.1371/journal.pone.0120489 |
Ejemplares similares
-
N-Glycan Branching Affects the Subcellular Distribution of and Inhibition of Matriptase by HAI-2/Placental Bikunin
por: Lai, Ying-Jung J., et al.
Publicado: (2015) -
Matriptase Complexes and Prostasin Complexes with HAI-1 and HAI-2 in Human Milk: Significant Proteolysis in Lactation
por: Lai, Chih-Hsin, et al.
Publicado: (2016) -
Differential subcellular distribution renders HAI-2 a less effective protease inhibitor than HAI-1 in the control of extracellular matriptase proteolytic activity
por: Chiu, Yi-Lin, et al.
Publicado: (2020) -
Tissue distribution and subcellular localizations determine in vivo functional relationship among prostasin, matriptase, HAI-1, and HAI-2 in human skin
por: Lee, Shiao-Pieng, et al.
Publicado: (2018) -
Correction: Tissue distribution and subcellular localizations determine in vivo functional relationship among prostasin, matriptase, HAI-1, and HAI-2 in human skin
por: Lee, Shiao-Pieng, et al.
Publicado: (2018)