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Escape from X Inactivation Varies in Mouse Tissues

X chromosome inactivation (XCI) silences most genes on one X chromosome in female mammals, but some genes escape XCI. To identify escape genes in vivo and to explore molecular mechanisms that regulate this process we analyzed the allele-specific expression and chromatin structure of X-linked genes i...

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Detalles Bibliográficos
Autores principales: Berletch, Joel B., Ma, Wenxiu, Yang, Fan, Shendure, Jay, Noble, William S., Disteche, Christine M., Deng, Xinxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364777/
https://www.ncbi.nlm.nih.gov/pubmed/25785854
http://dx.doi.org/10.1371/journal.pgen.1005079