The aged nonhematopoietic environment impairs natural killer cell maturation and function

Natural killer (NK) cells are critical in eliminating tumors and viral infections, both of which occur at a high incidence in the elderly. Previous studies showed that aged NK cells are less cytotoxic and exhibit impaired maturation compared to young NK cells. We evaluated whether extrinsic or intri...

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Detalles Bibliográficos
Autores principales: Shehata, Hesham M, Hoebe, Kasper, Chougnet, Claire A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364831/
https://www.ncbi.nlm.nih.gov/pubmed/25677698
http://dx.doi.org/10.1111/acel.12303

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