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Lymphocyte maintenance during healthy aging requires no substantial alterations in cellular turnover

In healthy humans, lymphocyte populations are maintained at a relatively constant size throughout life, reflecting a balance between lymphocyte production and loss. Given the profound immunological changes that occur during healthy aging, including a significant decline in T-cell production by the t...

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Detalles Bibliográficos
Autores principales: Westera, Liset, van Hoeven, Vera, Drylewicz, Julia, Spierenburg, Gerrit, van Velzen, Jeroen F, de Boer, Rob J, Tesselaar, Kiki, Borghans, José A M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364834/
https://www.ncbi.nlm.nih.gov/pubmed/25627171
http://dx.doi.org/10.1111/acel.12311