Response to the dipeptidyl peptidase-4 inhibitors in Japanese patients with type 2 diabetes might be associated with a diplotype of two single nucleotide polymorphisms on the interleukin-6 promoter region under a certain level of physical activity

AIMS/INTRODUCTION: Muscle-derived interleukin-6 (IL-6) has been reported to promote glucagon-like peptide-1 (GLP-1) secretion, and we explored the association of single nucleotide polymorphisms (SNPs) in the human IL-6 promoter region with the responsiveness to dipeptidyl peptidase-4 inhibitors (DPP...

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Detalles Bibliográficos
Autores principales: Matsui, Mizue, Takahashi, Yoshihiko, Takebe, Noriko, Takahashi, Kazuma, Nagasawa, Kan, Honma, Hiroyuki, Oda, Tomoyasu, Ono, Mitsutaka, Nakagawa, Riyuki, Sasai, Takayoshi, Togashi, Hirobumi, Hangai, Mari, Kajiwara, Takashi, Taneichi, Haruhito, Ishigaki, Yasushi, Satoh, Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364852/
https://www.ncbi.nlm.nih.gov/pubmed/25802725
http://dx.doi.org/10.1111/jdi.12260

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