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Combined Antigen-Specific Interferon-γ and Interleukin-2 Release Assay (FluoroSpot) for the Diagnosis of Mycobacterium tuberculosis Infection
BACKGROUND: To evaluate interleukin (IL)-2 and interferon (IFN)-γ secreting T-cells in parallel for the differentiation of latent infection with Mycobacterium tuberculosis infection (LTBI) from active tuberculosis. METHODS: Following ex-vivo stimulation of peripheral blood mononuclear cells (PBMC) w...
Autores principales: | Chesov, Dumitru, Lange, Christoph, Daduna, Franziska, Crudu, Valeriu, Preyer, Rosemarie, Ernst, Martin, Kalsdorf, Barbara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364905/ https://www.ncbi.nlm.nih.gov/pubmed/25785445 http://dx.doi.org/10.1371/journal.pone.0120006 |
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