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Mechanisms of Chemical Cooperative Carcinogenesis by Epidermal Langerhans Cells
Cutaneous squamous cell carcinoma (SCC) is the most prevalent invasive malignancy with metastatic potential. The epidermis is exposed to a variety of environmental DNA-damaging chemicals, principal among which are polyaromatic hydrocarbons (PAH) ubiquitous in the environment, tobacco smoke, and broi...
Autores principales: | Lewis, Julia M., Bürgler, Christina D., Fraser, Juliet A., Liao, Haihui, Golubets, Kseniya, Kucher, Cynthia L., Zhao, Peter Y., Filler, Renata B., Tigelaar, Robert E., Girardi, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364923/ https://www.ncbi.nlm.nih.gov/pubmed/25233073 http://dx.doi.org/10.1038/jid.2014.411 |
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