Inhibition of insulin/IGF-1 receptor signaling protects from mitochondria-mediated kidney failure

Mitochondrial dysfunction and alterations in energy metabolism have been implicated in a variety of human diseases. Mitochondrial fusion is essential for maintenance of mitochondrial function and requires the prohibitin ring complex subunit prohibitin-2 (PHB2) at the mitochondrial inner membrane. He...

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Detalles Bibliográficos
Autores principales: Ising, Christina, Koehler, Sybille, Brähler, Sebastian, Merkwirth, Carsten, Höhne, Martin, Baris, Olivier R, Hagmann, Henning, Kann, Martin, Fabretti, Francesca, Dafinger, Claudia, Bloch, Wilhelm, Schermer, Bernhard, Linkermann, Andreas, Brüning, Jens C, Kurschat, Christine E, Müller, Roman-Ulrich, Wiesner, Rudolf J, Langer, Thomas, Benzing, Thomas, Brinkkoetter, Paul Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364945/
https://www.ncbi.nlm.nih.gov/pubmed/25643582
http://dx.doi.org/10.15252/emmm.201404916

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