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Phosphorescence Monitoring of Hypoxic Microenvironment in Solid-Tumors to Evaluate Chemotherapeutic Effects Using the Hypoxia-Sensitive Iridium (III) Coordination Compound

OBJECTIVES: To utilize phosphorescence to monitor hypoxic microenvironment in solid-tumors and investigate cancer chemotherapeutic effects in vivo. METHODS: A hypoxia-sensitive probe named BTP was used to monitor hypoxic microenvironment in solid-tumors. The low-dose metronomic treatment with cispla...

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Detalles Bibliográficos
Autores principales:	Zeng, Yun, Liu, Yang, Shang, Jin, Ma, Jingwen, Wang, Rong, Deng, Lei, Guo, Youmin, Zhong, Fan, Bai, Mingfeng, Zhang, Shaojuan, Wu, Daocheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365010/ https://www.ncbi.nlm.nih.gov/pubmed/25786221 http://dx.doi.org/10.1371/journal.pone.0121293

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