Transport through recycling endosomes requires EHD1 recruitment by a phosphatidylserine translocase

P(4)-ATPases translocate aminophospholipids, such as phosphatidylserine (PS), to the cytosolic leaflet of membranes. PS is highly enriched in recycling endosomes (REs) and is essential for endosomal membrane traffic. Here, we show that PS flipping by an RE-localized P(4)-ATPase is required for the r...

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Detalles Bibliográficos
Autores principales: Lee, Shoken, Uchida, Yasunori, Wang, Jiao, Matsudaira, Tatsuyuki, Nakagawa, Takatoshi, Kishimoto, Takuma, Mukai, Kojiro, Inaba, Takehiko, Kobayashi, Toshihide, Molday, Robert S, Taguchi, Tomohiko, Arai, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365035/
https://www.ncbi.nlm.nih.gov/pubmed/25595798
http://dx.doi.org/10.15252/embj.201489703

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